SCHEMBL10485237

SCHEMBL10485237

CC1CCC2(CC1)CC1(CCC(C)CC1)C2

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24309070 0.86 KDM4E (0.32) KDM4EPKM
SCHEMBL10485114 0.83
SCHEMBL10485105 0.83
SCHEMBL3021931 0.83
SCHEMBL10484716 0.79 MEN1 (0.32)
SCHEMBL3013631 0.78
SCHEMBL20627354 0.78 APOBEC3A (0.30)
SCHEMBL5565339 0.75 ACHE (0.30)
SCHEMBL24066446 0.73
SCHEMBL5598932 0.73 KDM4E (0.35) KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0248861-B1 DISPIROTETRADECANE MERCK PATENT GmbH (DE) 1989-08-16 EP disclosed
US-4853151-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKFTER HAFTUNG (DE) 1989-08-01 US disclosed