SCHEMBL5598932

SCHEMBL5598932

CC1CCC2(CC1)COC2

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15987017 0.84
SCHEMBL16659518 0.82 KDM4E (0.32) KDM4EPKM
SCHEMBL30720 0.79 KDM4E (0.33) KDM4EPKM
SCHEMBL19455050 0.79 PRMT1 (0.32) KDM4EPKM
SCHEMBL19454920 0.79 PRMT1 (0.32) KDM4EPKM
SCHEMBL19455053 0.79 PRMT1 (0.32) KDM4EPKM
SCHEMBL24309070 0.78 KDM4E (0.32) KDM4EPKM
SCHEMBL13380860 0.76 CYP1A2 (0.33) KDM4EPKM
SCHEMBL3021931 0.76
SCHEMBL16604736 0.74 KDM4E (0.37) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044183-A1 FUSED HETEROBICYCLIC ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed
EP-4310084-A1 PYRIDOPYRIMIDINE-BASED COMPOUND AND APPLICATION THEREOF Jinan University (CN) 2024-01-24 EP disclosed
EP-4245756-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF Gilead Sciences, Inc. (US) 2023-09-20 EP disclosed
EP-4209485-A1 COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF Innovstone Therapeutics Limited (CN) 2023-07-12 EP disclosed
WO-2023125708-A1 P38 MAPK/MK2 PATHWAY MODULATOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海美悦生物科技发展有限公司 2023-07-06 WO disclosed
WO-2023122581-A2 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-06-29 WO disclosed
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) 2023-06-01 US disclosed
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) 2023-06-01 US disclosed
WO-2023076237-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. (US) 2023-05-04 WO disclosed
US-20230133132-A1 NAMPT MODULATORS CYTOKINETICS, INC. 2023-05-04 US disclosed
WO-2017062581-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR PROTEOSTASIS THERAPEUTICS, INC. (US) 2017-04-13 WO disclosed
US-9226923-B2 Spirocyclic molecules as protein kinase inhibitors NANJING ALLGEN PHARMA CO. LTD. (CN) 2016-01-05 US disclosed
WO-2015172747-A1 SPIROCYCLIC MOLECULES AS MTH1 INHIBITORS WANG ZHAOYIN (CN) 2015-11-19 WO disclosed
US-20140243303-A1 SPIROCYCLIC MOLECULES AS PROTEIN KINASE INHIBITORS BETA PHARMA CANADA INC. (CA) 2014-08-28 US disclosed
EP-1237983-B1 POLYMERIZABLE COMPOSITION, CURED MATERIAL THEREOF AND METHOD FOR MANUFACTURING THE SAME SHOWA DENKO KK (JP) 2007-08-01 EP disclosed
US-6783840-B2 FOR PRODUCING PRINTED CIRCUIT BOARD SHOWA DENKO K.K. (JP) 2004-08-31 US disclosed
US-20030022958-A1 Resist ink composition SHOWA DENKO K.K. (JP) 2003-01-30 US disclosed
US-20020161068-A1 Polymerizable composition, cured material thereof and method for manufacturing the same SHOWA DENKO K.K. (JP) 2002-10-31 US disclosed
EP-1222496-A1 RESIST INK COMPOSITION Showa Denko K.K. (JP) 2002-07-17 EP disclosed
WO-2002008347-A2 RESIST INK COMPOSITION SHOWA DENKO K. K. (JP) 2002-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133132-A1 NAMPT MODULATORS NAMPT, MC4R, SIRT1 KDM4E 2721/4885PKM 401/4885
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF SYMPK, PAICS, CYP2C9 KDM4E 3146/4885PKM 72/4885
US-20140243303-A1 SPIROCYCLIC MOLECULES AS PROTEIN KINASE INHIBITORS MET, RET, ALK KDM4E 1118/4885PKM 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.