Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760473 | 0.83 | ALOX5 (0.53) | — | |
| SCHEMBL30057865 | 0.83 | MEN1 (0.43) | GLSALDH1A1KDM4ETP53CASP3 | |
| SCHEMBL10484937 | 0.77 | GLS (0.62) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL10484833 | 0.74 | GLS (0.68) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL22633704 | 0.74 | GLS (0.68) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL12862597 | 0.72 | GLS (0.57) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL14884718 | 0.72 | GLS (0.57) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL4322902 | 0.71 | GLS (0.64) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL3002007 | 0.71 | GLS (0.55) | GLSTSHRALDH1A1KDM4ETP53 | |
| SCHEMBL30583194 | 0.71 | GLS (0.64) | GLSTSHRALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861778-A | 2,3-dihydrophthalazine-1,4-diones | RESEARCH CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |