Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128795 | 0.86 | POLB (0.53) | TRPV1KDM4EATMPOLBMAPT | |
| SCHEMBL9128784 | 0.86 | POLB (0.53) | TRPV1KDM4EATMPOLBMAPT | |
| SCHEMBL9288443 | 0.83 | POLB (0.50) | TRPV1KDM4EATMPOLBKMT2A | |
| SCHEMBL11052318 | 0.83 | POLB (0.50) | TRPV1KDM4EATMPOLBKMT2A | |
| SCHEMBL10485741 | 0.81 | KDM4E (0.54) | TRPV1KDM4EATMPOLBMAPT | |
| SCHEMBL9632958 | 0.80 | PPARG (0.56) | KDM4EATMPOLBKMT2AMAPT | |
| SCHEMBL9632951 | 0.80 | PPARG (0.56) | KDM4EATMPOLBKMT2AMAPT | |
| SCHEMBL11056507 | 0.80 | TRPV1 (0.54) | TRPV1KMT2AALDH1A1 | |
| SCHEMBL11056487 | 0.80 | TRPV1 (0.54) | TRPV1KMT2AALDH1A1 | |
| SCHEMBL21839348 | 0.78 | PPARG (0.56) | KDM4EKMT2AMAPTALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | disclosed |