Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052318 | 1.00 | POLB (0.50) | POLBALDH1A1GLATDP1L3MBTL1 | |
| SCHEMBL9128795 | 0.97 | POLB (0.53) | POLBALDH1A1GLATDP1L3MBTL1 | |
| SCHEMBL9128784 | 0.97 | POLB (0.53) | POLBALDH1A1GLATDP1L3MBTL1 | |
| Farnesol SCHEMBL28074103 | 0.84 | MAPT (0.65) | POLBALDH1A1TRPA1MAPTICMT | |
| SCHEMBL11056507 | 0.84 | TRPV1 (0.54) | ALDH1A1TRPV1KMT2A | |
| SCHEMBL11056487 | 0.84 | TRPV1 (0.54) | ALDH1A1TRPV1KMT2A | |
| SCHEMBL10486138 | 0.83 | TRPV1 (0.46) | POLBALDH1A1MAPTTRPV1KMT2A | |
| SCHEMBL10485741 | 0.82 | KDM4E (0.54) | POLBALDH1A1TRPA1MAPTICMT | |
| SCHEMBL11050799 | 0.82 | TRPV1 (0.62) | ALDH1A1LMNACYP1A2CYP3A4TRPV1 | |
| SCHEMBL11053785 | 0.82 | LMNA (0.54) | POLBALDH1A1GLATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482734-A | ANTICANCER, ANTIINFLAMMATORY, ANTIALLERGENS AND TREATMENT OF SKIN DISORDERS | EISAI CO., LTD. (JP) | 1984-11-13 | — | — | US | claimed |
| JP-7258150-A | — | — | None | — | — | JP | disclosed |
| JP-H07258150-A | THERAPEUTIC AGENT FOR HTLV-I INFECTION | EISAI CO LTD | 1995-10-09 | — | — | JP | disclosed |
| EP-0110397-B1 | POLYPRENYL COMPOUND AND DRUG CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4762829-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| US-4742058-A | AMIDES, ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4482734-A | ANTICANCER, ANTIINFLAMMATORY, ANTIALLERGENS AND TREATMENT OF SKIN DISORDERS | EISAI CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |
| EP-0110397-A2 | Polyprenyl compound and drug containing the same | Eisai Co., Ltd. (JP) | 1984-06-13 | — | — | EP | disclosed |