Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10485620 | 0.99 | KCNH2 (0.68) | KCNH2MAPTKMT2AHTR7RECQL | |
| SCHEMBL10485775 | 0.94 | MAPT (0.79) | KCNH2MAPTKMT2AHTR7RECQL | |
| SCHEMBL10486120 | 0.94 | MAPT (0.65) | KCNH2MAPTKMT2AHTR7RECQL | |
| SCHEMBL10700125 | 0.94 | HTR1A (0.67) | KCNH2MAPTKMT2AHTR7RECQL | |
| SCHEMBL10485665 | 0.94 | HTR1A (0.67) | KCNH2MAPTKMT2AHTR7RECQL | |
| SCHEMBL10485697 | 0.94 | KMT2A (0.69) | KCNH2MAPTKMT2AHTR7RECQL | |
| SCHEMBL10485776 | 0.94 | KMT2A (0.76) | KCNH2MAPTKMT2AHTR7RECQL | |
| Hydrochloric Acid SCHEMBL10485594 | 0.93 | MAPT (0.64) | KCNH2MAPTKMT2AHTR7RECQL | |
| Hydrochloric Acid SCHEMBL10485836 | 0.93 | MAPT (0.77) | KCNH2MAPTKMT2AHTR7LMNA | |
| Hydrochloric Acid SCHEMBL10485627 | 0.92 | HTR1A (0.64) | KCNH2MAPTKMT2AHTR7RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882330-A | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-11-21 | — | — | US | claimed |
| EP-0269383-A2 | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-01 | — | — | EP | claimed |