SCHEMBL10486205

SCHEMBL10486205

C=C=CC(C)(O)CCCC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27641673 0.92 FDPS (0.38)
SCHEMBL31303662 0.92 FDPS (0.38)
SCHEMBL13384409 0.75
SCHEMBL28857285 0.75
SCHEMBL5872624 0.74 ALOX15 (0.38) ALOX15MEN1CYP3A4KMT2A
SCHEMBL5872626 0.74 ALOX15 (0.38) ALOX15MEN1CYP3A4KMT2A
SCHEMBL31303621 0.72 ALOX15 (0.64) ALOX15MEN1CYP3A4KMT2A
SCHEMBL31303611 0.72 ALOX15 (0.64) ALOX15MEN1CYP3A4KMT2A
SCHEMBL11268801 0.71
SCHEMBL11664072 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4833157-A ANTIULCER AGENTS MILES INC. (US) 1989-05-23 US disclosed
US-4742080-A Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters MILES LABORATORIES, INC. (US) 1988-05-03 US disclosed
EP-0066475-B1 PHARMACEUTICAL COMPOSITION FOR USE IN INDUCING CYTOPROTECTION ORTHO PHARMACEUTICAL CORPORATION (US) 1986-10-01 EP disclosed
US-4415592-A ANTISECRETORY AND HYPOTENSIVE AGENTS MILES LABORATORIES, INC. (US) 1983-11-15 US disclosed
US-4370348-A USING A PROSTAGLANDIN DERIVATIVE ORTHO PHARMACEUTICAL CORPORATION (US) 1983-01-25 US disclosed
US-4331688-A Therapeutic method for inhibiting gastric secretion by administration of 15-deoxy-16-hydroxy prostaglandins MILES LABORATORIES, INC. (US) 1982-05-25 US disclosed
US-4275224-A BRONCHODIALATORS AND ANTI-GASTRIC SECRETION AGENTS MILES LABORATORIES, INC. (US) 1981-06-23 US disclosed
US-4132738-A BRONCHODILATORS, ANTISECRETORY AGENTS MILES LABORATORIES, INC. (US) 1979-01-02 US disclosed