SCHEMBL10486285

SCHEMBL10486285

CC=CC(=O)OCCC[SiH2]CC(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 4/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340894 0.85 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL339523 0.82 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL22092322 0.82 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL35613 0.81 ATM (0.40) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL19972135 0.78
SCHEMBL10486302 0.77 TSHR (0.45) TSHR
SCHEMBL29161421 0.76 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7878196 0.75 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3349593 0.74 ATM (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10627158 0.74 ATM (0.48) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4839109-A Process for producing a contact lens JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1989-06-13 US disclosed