SCHEMBL35613

SCHEMBL35613

CC=CC(=O)OCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
HCAR2 Q8TDS4 4/20 0.36
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 2/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21050107 0.90 ALDH1A1 (0.33) ATMTSHRALDH1A1
SCHEMBL331865 0.86
SCHEMBL341121 0.84 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL394436 0.83 TSHR (0.50) ATMHCAR2TSHRHPGDALDH1A1
SCHEMBL28074015 0.83 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL676304 0.82 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL15402551 0.82 ATM (0.40) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9093138 0.82 ATM (0.40) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL663826 0.81
SCHEMBL10486285 0.81 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
US-20250368802-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY CANON KK (JP) 2025-12-04 US claimed
EP-4526381-A1 SILICONE HYDROGEL CONTACT LENSES Interojo Inc. (KR) 2025-03-26 EP claimed
US-20240199816-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-20 US claimed
WO-2024123531-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-13 WO claimed
US-20240159938-A1 Compositions for Ophthalmologic Devices JOHNSON & JOHNSON VISION CARE, INC. 2024-05-16 US claimed
US-20230374307-A1 SILICONE HYDROGEL CONTACT LENSES INTEROJO INC. (KR) 2023-11-23 US claimed
WO-2023224184-A1 SILICONE HYDROGEL CONTACT LENSES INTEROJO INC. (KR) 2023-11-23 WO claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-11360241-B2 Biomedical devices containing internal wetting agents JOHNSON & JOHNSON VISION CARE, INC. (US) 2022-06-14 US claimed
WO-2003022322-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
WO-2003022321-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
US-6383502-B1 Non-stinging coating composition 3M INNOVATIVE PROPERTIES COMPANY 2002-05-07 US claimed
US-6031059-A POLYMERIZING A HYDROPHOBIC SILOXANE PREPOPLYMER AND A SILYLATED HYDROPHILIC MONOMER AND HYDROLYZING THE RESULTING POLYMER WHEREIN POLYMERIZING IS CARRIED OUT BY USING ONE OF HEAT POLYMERIZATION, ULTRAVIOLET LIGHT JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 2000-02-29 US claimed
US-5962548-A SOFT CONTACT LENSES JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1999-10-05 US claimed
US-5770669-A Silcone-containing polymer having oxygen permeability suitable for ophalmic applications CIBA VISION CORPORATION (US) 1998-06-23 US claimed
EP-0796448-A1 SILICONE-CONTAINING POLYMER SUITABLE FOR OPHTHALMIC APPLICATIONS Novartis AG (CH) 1997-09-24 EP claimed
WO-1996018122-A1 SILICONE-CONTAINING POLYMER SUITABLE FOR OPHTHALMIC APPLICATIONS NOVARTIS AG (CH) 1996-06-13 WO claimed
EP-0277555-B1 COPOLYMERS WITH 0-NITROCARBINOL ESTER GROUPS, AND PROCESS FOR PREPARING TWO-LAYER RESISTS AND SEMICONDUCTOR DEVICES BASF Aktiengesellschaft (DE) 1992-04-08 EP claimed
US-4808682-A BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1989-02-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600820-B2 Photocurable composition with high silicon content BIRC2, ACP1, IRS1 ATM 351/4885HCAR2 2899/4885MAPT 2167/4885
US-20240159938-A1 Compositions for Ophthalmologic Devices PDE6D, CRYAB, PDE6H ATM 2249/4885HCAR2 3044/4885MAPT 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.