Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16537954 | 0.83 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5702095 | 0.82 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35615 | 0.81 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537556 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28355806 | 0.81 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29198317 | 0.81 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18114635 | 0.79 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16535968 | 0.79 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL397027 | 0.78 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28352181 | 0.78 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839109-A | Process for producing a contact lens | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1989-06-13 | — | — | US | disclosed |