Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29198317 | 0.83 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1358595 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1046104 | 0.80 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL919922 | 0.80 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10486302 | 0.79 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29172991 | 0.78 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL434075 | 0.78 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26078840 | 0.78 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22371483 | 0.77 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31264359 | 0.77 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274384-A1 | VINYL-BASED SILICONE-SUBSTITUTED HYDROPHILIC COPOLYMER AND HYDROGEL COMPOSITION COMPRISING THE SAME | Momentive Performance Materials Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016160488-A1 | VINYL-BASED SILICONE-SUBSTITUTED HYDROPHILIC COPOLYMER AND HYDROGEL COMPOSITION COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-10-06 | — | — | WO | disclosed |