Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883024 | 0.92 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5202793 | 0.91 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL396935 | 0.91 | THRB (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5575873 | 0.90 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3478204 | 0.86 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL30386461 | 0.86 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL331867 | 0.84 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL136875 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9354424 | 0.82 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5068019 | 0.82 | TSHR (0.35) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121610138-B | Fluorine-free silicon-containing anti-icing coating regulated and controlled based on organic tellurium compound and preparation method thereof | 西北工业大学 | 2026-05-19 | — | — | CN | claimed |
| US-12600820-B2 | Photocurable composition with high silicon content | CANON KABUSHIKI KAISHA (JP) | 2026-04-14 | — | — | US | claimed |
| US-20250368802-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY | CANON KK (JP) | 2025-12-04 | — | — | US | claimed |
| US-12448516-B2 | Silicone hydrogel contact lenses | INTEROJO INC. (KR) | 2025-10-21 | — | — | US | claimed |
| EP-4526381-A1 | SILICONE HYDROGEL CONTACT LENSES | Interojo Inc. (KR) | 2025-03-26 | — | — | EP | claimed |
| CN-119505241-A | Method for preparing silicon-containing prepolymer, silicon-containing prepolymer and silicon hydrogel film | 摩尔应材有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-118930724-A | Hydrogel lens and preparation method thereof | 海昌隐形眼镜有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118546290-A | Solvent-free photo-curing organic silicon acrylate polymer pressure-sensitive adhesive and preparation method thereof | 国科广化(南雄)新材料研究院有限公司 | 2024-08-27 | — | — | CN | claimed |
| US-20240199816-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT | CANON KABUSHIKI KAISHA (JP) | 2024-06-20 | — | — | US | claimed |
| WO-2024123531-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT | CANON KABUSHIKI KAISHA (JP) | 2024-06-13 | — | — | WO | claimed |
| US-6383502-B1 | Non-stinging coating composition | 3M INNOVATIVE PROPERTIES COMPANY | 2002-05-07 | — | — | US | claimed |
| US-6031059-A | POLYMERIZING A HYDROPHOBIC SILOXANE PREPOPLYMER AND A SILYLATED HYDROPHILIC MONOMER AND HYDROLYZING THE RESULTING POLYMER WHEREIN POLYMERIZING IS CARRIED OUT BY USING ONE OF HEAT POLYMERIZATION, ULTRAVIOLET LIGHT | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 2000-02-29 | — | — | US | claimed |
| US-5998498-A | SILICONE HYDROGEL | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-12-07 | — | — | US | claimed |
| US-5962548-A | SOFT CONTACT LENSES | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-0940693-A2 | Soft contact lenses | Johnson & Johnson Vision Products, Inc. (US) | 1999-09-08 | — | — | EP | claimed |
| US-5770669-A | Silcone-containing polymer having oxygen permeability suitable for ophalmic applications | CIBA VISION CORPORATION (US) | 1998-06-23 | — | — | US | claimed |
| EP-0796448-A1 | SILICONE-CONTAINING POLYMER SUITABLE FOR OPHTHALMIC APPLICATIONS | Novartis AG (CH) | 1997-09-24 | — | — | EP | claimed |
| WO-1996018122-A1 | SILICONE-CONTAINING POLYMER SUITABLE FOR OPHTHALMIC APPLICATIONS | NOVARTIS AG (CH) | 1996-06-13 | — | — | WO | claimed |
| EP-0277555-B1 | COPOLYMERS WITH 0-NITROCARBINOL ESTER GROUPS, AND PROCESS FOR PREPARING TWO-LAYER RESISTS AND SEMICONDUCTOR DEVICES | BASF Aktiengesellschaft (DE) | 1992-04-08 | — | — | EP | claimed |
| US-4808682-A | BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600820-B2 | Photocurable composition with high silicon content | BIRC2, ACP1, IRS1 | TSHR 4173/4885THRB 4666/4885POLB 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.