Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.81 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486431 | 1.00 | PTGIR (0.81) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL7587667 | 0.94 | PTGIR (0.84) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL14366538 | 0.94 | PTGIR (0.84) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL13143656 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL13179799 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL23352984 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL13951097 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL23352757 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL14273618 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL7586616 | 0.88 | PTGIR (0.64) | PTGIRPTGER2TSHRPTGER4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415592-A | ANTISECRETORY AND HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1983-11-15 | — | — | US | claimed |
| US-4833157-A | ANTIULCER AGENTS | MILES INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4742080-A | Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters | MILES LABORATORIES, INC. (US) | 1988-05-03 | — | — | US | disclosed |
| US-4415592-A | ANTISECRETORY AND HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4331688-A | Therapeutic method for inhibiting gastric secretion by administration of 15-deoxy-16-hydroxy prostaglandins | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4275224-A | BRONCHODIALATORS AND ANTI-GASTRIC SECRETION AGENTS | MILES LABORATORIES, INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4132738-A | BRONCHODILATORS, ANTISECRETORY AGENTS | MILES LABORATORIES, INC. (US) | 1979-01-02 | — | — | US | disclosed |