Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.84 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.84 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366538 | 1.00 | PTGIR (0.84) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL10486377 | 0.94 | PTGIR (0.81) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL10486431 | 0.94 | PTGIR (0.81) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL13143656 | 0.91 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL14273618 | 0.91 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL23352984 | 0.91 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL23352757 | 0.91 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL13951097 | 0.91 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| SCHEMBL13179799 | 0.91 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA | |
| Butaprost SCHEMBL23353211 | 0.89 | PTGIR (1.00) | PTGIRPTGER2TSHRABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | claimed |