Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326448 | 1.00 | RAD52 (0.39) | RAD52OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10486749 | 1.00 | RAD52 (0.39) | RAD52OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9351938 | 0.92 | KDM4E (0.40) | RAD52OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9329224 | 0.80 | OPRM1 (0.38) | RAD52OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9326406 | 0.77 | OPRM1 (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL77388 | 0.77 | POLB (0.33) | — | |
| SCHEMBL10664933 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL13508232 | 0.77 | OPRM1 (0.40) | RAD52OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10486753 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9488985 | 0.75 | RAD52 (0.54) | RAD52KDM4ELMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4841053-A | Process for desensitizing a 1-(alkylamino)alkyl-polysubstituted piperazinone during recovery | THE B. F. GOODRICH COMPANY (US) | 1989-06-20 | — | — | US | disclosed |