Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PROC | P04070 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588409 | 0.75 | MME (0.41) | F2PROCMMELTA4HALDH1A1 | |
| SCHEMBL5634108 | 0.74 | MME (0.38) | F2PROCMMEALDH1A1LMNA | |
| SCHEMBL7386060 | 0.71 | MME (0.38) | F2PROCMMEALDH1A1LMNA | |
| SCHEMBL7104488 | 0.68 | NPSR1 (0.34) | F2PROCMMEALDH1A1LMNA | |
| SCHEMBL6864504 | 0.68 | MME (0.33) | F2PROCMME | |
| SCHEMBL4323492 | 0.67 | DPP4 (0.47) | MMEALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL1782571 | 0.67 | MME (0.33) | F2PROCMMEALDH1A1MAPT | |
| SCHEMBL1568710 | 0.66 | MME (0.35) | MMEALDH1A1 | |
| SCHEMBL5095243 | 0.66 | TSHR (0.41) | F2PROCMMEALDH1A1LMNA | |
| SCHEMBL1781639 | 0.66 | DPP4 (0.49) | MMEALDH1A1LMNAUSP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820729-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |