Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PROC | P04070 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568710 | 0.91 | MME (0.35) | MMECYP2C19ALDH1A1 | |
| SCHEMBL14398111 | 0.83 | CYP2C19 (0.33) | MMECYP2C19CYP1A2LTA4HALDH1A1 | |
| SCHEMBL5634108 | 0.81 | MME (0.38) | MMECYP2C19F2PROCCYP1A2 | |
| SCHEMBL7386060 | 0.81 | MME (0.38) | MMECYP2C19F2PROCCYP1A2 | |
| SCHEMBL5673887 | 0.77 | CYP2C19 (0.35) | MMECYP2C19CYP1A2LTA4HALDH1A1 | |
| SCHEMBL4616715 | 0.76 | CYP2C19 (0.39) | CYP2C19CYP1A2LTA4HALDH1A1USP2 | |
| SCHEMBL10487590 | 0.75 | F2 (0.36) | MMEF2PROCCYP1A2LTA4H | |
| SCHEMBL11512482 | 0.74 | SMN1; SMN2 (0.38) | CYP2C19CYP1A2LTA4HALDH1A1USP2 | |
| SCHEMBL6864504 | 0.74 | MME (0.33) | MMEF2PROC | |
| SCHEMBL7104488 | 0.74 | NPSR1 (0.34) | MMECYP2C19F2PROCCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569327-B1 | EIF4E BINDING PEPTIDES | AGENCY SCIENCE TECH & RES (SG) | 2016-05-25 | — | — | EP | claimed |
| EP-2569327-A1 | EIF4E BINDING PEPTIDES | Agency For Science, Technology And Research (SG) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011136744-A1 | EIF4E BINDING PEPTIDES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-11-03 | — | — | WO | disclosed |