Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PROC | P04070 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386060 | 0.80 | MME (0.38) | MMECYP2C19ALDH1A1F2PROC | |
| SCHEMBL5634108 | 0.77 | MME (0.38) | MMEMAPTCYP2C19ALDH1A1F2 | |
| SCHEMBL2588409 | 0.74 | MME (0.41) | MMECYP2C19ALDH1A1F2PROC | |
| SCHEMBL1782571 | 0.72 | MME (0.33) | MMEMAPTCYP2C19ALDH1A1L3MBTL1 | |
| Water SCHEMBL6244439 | 0.71 | MME (0.32) | MMEMAPTCYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL15764684 | 0.70 | NPSR1 (0.38) | NPSR1CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL6864504 | 0.70 | MME (0.33) | NPSR1MMEF2PROC | |
| SCHEMBL5101551 | 0.69 | NPSR1 (0.43) | NPSR1MAPTCYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL1781639 | 0.69 | DPP4 (0.49) | MMECYP2C19EGLN1ALDH1A1PTGDR | |
| SCHEMBL10487590 | 0.68 | F2 (0.36) | MMEMAPTALDH1A1F2PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078436-A1 | Process for the catalytic preparation of N-acylglycine derivatives | GEISSLER HOLGER (DE) | 2003-04-24 | — | — | US | disclosed |
| EP-0918745-B1 | CATALYTIC PREPARATION PROCESS OF N-ACYLGLYCINE DERIVATIVES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-28 | — | — | EP | disclosed |
| US-20010007911-A1 | CATALYTIC PREPARATION PROCESS OF N-ACYLGLYCINE DERIVATIVES | AVENTIS RESEARCH & TECHNOLOGIES DEUTCHLAND GMBH & CO. KG. (DE) | 2001-07-12 | — | — | US | disclosed |
| EP-0918745-A1 | CATALYTIC PREPARATION PROCESS OF N-ACYLGLYCINE DERIVATIVES | Aventis Research & Technologies GmbH & Co KG (DE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004518-A1 | CATALYTIC PREPARATION PROCESS OF N-ACYLGLYCINE DERIVATIVES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007911-A1 | CATALYTIC PREPARATION PROCESS OF N-ACYLGLYCINE DERIVATIVES | ACACA, ACOX1, APEH | NPSR1 3078/4885MME 2698/4885MAPT 4847/4885 |
| US-20030078436-A1 | Process for the catalytic preparation of N-acylglycine derivatives | GNMT, ALKBH3, DDC | NPSR1 2315/4885MME 1316/4885MAPT 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.