Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487655 | 1.00 | THRA (0.38) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL7945365 | 0.90 | THRA (0.39) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL7943884 | 0.90 | THRA (0.39) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL9068449 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL6058927 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL7522466 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL10775029 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL7529783 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL98963 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL6058721 | 0.78 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888371-A | HEAT RESISTANCE, LIGHT RESISTANCE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1989-12-19 | — | — | US | disclosed |
| EP-0255097-A2 | Process for improving resistance to deterioration when exposed to sterilizing radiation of polyolefin resins | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1988-02-03 | — | — | EP | disclosed |
| EP-0143464-B1 | PENTAERYTHRITOL-SPIRO-BIS-PHOSPHITE COMPOSITIONS HAVING IMPROVED HYDROLYTIC STABILITY | Argus Chemical Corporation (US) | 1987-07-08 | — | — | EP | disclosed |
| EP-0143464-A2 | Pentaerythritol-spiro-bis-phosphite compositions having improved hydrolytic stability | Argus Chemical Corporation (US) | 1985-06-05 | — | — | EP | disclosed |