Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487698 | 0.89 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL10487755 | 0.88 | SMN1; SMN2 (0.43) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10487610 | 0.87 | ALDH1A1 (0.44) | KMT2AKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10487782 | 0.85 | LMNA (0.43) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL10607211 | 0.84 | PIM3 (0.37) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9076418 | 0.80 | SMN1; SMN2 (0.46) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL2963423 | 0.79 | SMN1; SMN2 (0.45) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL305861 | 0.79 | MEN1 (0.49) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL10608505 | 0.77 | ALDH1A1 (0.45) | KMT2AKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11676843 | 0.77 | SMN1; SMN2 (0.44) | KDM4EALDH1A1TSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206635-B1 | PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4835306-A | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |