Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 17/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488200 | 0.92 | ADRB2 (0.62) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488222 | 0.92 | ADRB2 (0.55) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488179 | 0.87 | ADRB2 (0.60) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10706286 | 0.87 | ADRB2 (0.66) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488210 | 0.83 | ADRB2 (0.62) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488196 | 0.83 | ADRB2 (0.65) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL9760113 | 0.82 | ADRB3 (0.55) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488093 | 0.82 | ADRB2 (0.58) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488552 | 0.82 | ADRB2 (0.64) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL10488537 | 0.82 | ADRB2 (0.61) | ADRB2CHRM3ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |