Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | ESR1 | P03372 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49950 | 0.90 | ALDH1A1 (0.84) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL5028692 | 0.89 | ESR1 (0.72) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL27647510 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL27667922 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL27647586 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL27647504 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL27647501 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL28758641 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| SCHEMBL27667930 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Methane SCHEMBL27699232 | 0.88 | ALDH1A1 (0.81) | ALDH1A1ESR1TSHRTDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321619-B | 8- (diphenylethynyl) -ester group-containing boron-fluorine pyrrole compound and synthesis and application thereof | 大连理工大学 | 2022-02-25 | — | — | CN | claimed |
| CN-112321619-A | 8- (diphenylethynyl) -ester group-containing boron-fluorine pyrrole compound and synthesis and application thereof | 大连理工大学 | 2021-02-05 | — | — | CN | claimed |
| CN-1016246-B | Process for preparing aminophenol derivatives | GLAXO GROUP LTD (GB) | 1992-04-15 | — | — | CN | disclosed |
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |