Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.72 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | STS | P08842 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907665 | 0.95 | ALDH1A1 (0.69) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL16422182 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL3386629 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL15962622 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL28524896 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL23496578 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL29196107 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL37476 | 0.91 | ESR1 (0.85) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL10488203 | 0.89 | ALDH1A1 (0.70) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL17737140 | 0.89 | ALDH1A1 (0.66) | ESR1TSHRLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321619-B | 8- (diphenylethynyl) -ester group-containing boron-fluorine pyrrole compound and synthesis and application thereof | 大连理工大学 | 2022-02-25 | — | — | CN | claimed |
| CN-112321619-A | 8- (diphenylethynyl) -ester group-containing boron-fluorine pyrrole compound and synthesis and application thereof | 大连理工大学 | 2021-02-05 | — | — | CN | claimed |
| US-20230339915-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| CN-108349930-A | Substituted Tricycles and Methods of Use | 艾伯维公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2014111574-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE, AN ORGANIC UVB-SCREENING AGENT AND AN ADDITIONAL ORGANIC UVA-SCREENING AGENT | L'OREAL (FR) | 2014-07-24 | — | — | WO | disclosed |
| US-8623833-B2 | Compositions and methods for enhancing drug delivery across and into epithelial tissues | KAI PHARMACEUTICALS, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-7459263-B2 | Optical recording media with triplet-sensitized isomerization | EASTMAN KODAK COMPANY (US) | 2008-12-02 | — | — | US | disclosed |
| US-20050136357-A1 | Optical recording media with triplet-sensitzed isomerization | FPC INC. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339915-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | SERPINA2, SERPINA3, SERPINB1 | ESR1 4727/4885TSHR 1985/4885LMNA 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.