Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.65 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456614 | 0.90 | SIGMAR1 (0.80) | SIGMAR1BCHEMAOACHRM2CNR1 | |
| SCHEMBL9666404 | 0.90 | SIGMAR1 (0.74) | SIGMAR1BCHEMAOACHRM2TDP1 | |
| Bromide SCHEMBL9578037 | 0.89 | SIGMAR1 (0.72) | SIGMAR1BCHEMAOACHRM2TDP1 | |
| Hydrochloric Acid SCHEMBL9260556 | 0.89 | SIGMAR1 (0.72) | SIGMAR1BCHEMAOACHRM2TDP1 | |
| Bromide SCHEMBL7121198 | 0.89 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2CNR1 | |
| Hydrochloric Acid SCHEMBL9254084 | 0.89 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2CNR1 | |
| Hydrochloric Acid SCHEMBL454214 | 0.89 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2CNR1 | |
| SCHEMBL27496896 | 0.89 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2CNR1 | |
| Hydrochloric Acid SCHEMBL9257562 | 0.89 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2CNR1 | |
| Hydrochloric Acid SCHEMBL9254761 | 0.87 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |