Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763073 | 0.85 | KDM4E (0.78) | KDM4EMCL1ALDH1A1RXFP1HPGD | |
| SCHEMBL14541242 | 0.81 | CA12 (0.58) | KDM4EALDH1A1RXFP1HPGDNPC1 | |
| SCHEMBL9989066 | 0.79 | KDM4E (0.80) | KDM4EMCL1ALDH1A1GPR35HPGD | |
| SCHEMBL8696622 | 0.78 | KDM4E (0.74) | KDM4EMCL1ALDH1A1GPR35HPGD | |
| SCHEMBL1065472 | 0.78 | MCL1 (0.71) | KDM4EMCL1ALDH1A1GPR35HPGD | |
| SCHEMBL10735951 | 0.77 | MCL1 (0.65) | KDM4EMCL1ALDH1A1GPR35HPGD | |
| SCHEMBL11465493 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1RXFP1HPGDNPC1 | |
| SCHEMBL5287590 | 0.76 | MCL1 (0.69) | KDM4EMCL1ALDH1A1GPR35HPGD | |
| SCHEMBL8697696 | 0.76 | KDM4E (0.70) | KDM4EMCL1ALDH1A1GPR35HPGD | |
| SCHEMBL4310466 | 0.75 | MCL1 (0.67) | KDM4EMCL1ALDH1A1GPR35RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1199957-A | — | — | None | — | — | JP | disclosed |
| JP-H01199957-A | BENZOFURAN DERIVATIVE, CHROMENE DERIVATIVE AND MEDICINE THEREFROM | MITSUI PETROCHEM IND LTD | 1989-08-11 | — | — | JP | disclosed |