Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.80 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621954 | 0.86 | KDM4E (0.67) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26602361 | 0.86 | KDM4E (0.67) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11455895 | 0.86 | KDM4E (0.64) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8696622 | 0.83 | KDM4E (0.74) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31453064 | 0.82 | KDM4E (0.62) | KDM4EMCL1NPC1RAB9AALDH1A1 | |
| SCHEMBL4763073 | 0.81 | KDM4E (0.78) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31453042 | 0.81 | KDM4E (0.60) | KDM4EMCL1NPC1RAB9AGAA | |
| SCHEMBL31453039 | 0.81 | KDM4E (0.60) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8697696 | 0.81 | KDM4E (0.70) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10488237 | 0.79 | KDM4E (0.68) | KDM4EMCL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |