Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10488357 | 0.99 | CD274 (0.36) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488837 | 0.90 | KMT2A (0.38) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL10488883 | 0.89 | KMT2A (0.40) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL10349542 | 0.88 | NPBWR1 (0.40) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488250 | 0.86 | KMT2A (0.38) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488373 | 0.86 | SLC2A1 (0.40) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL10488310 | 0.85 | SLC2A1 (0.42) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL10488570 | 0.85 | KMT2A (0.40) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488900 | 0.84 | KIF11 (0.35) | CD274SLC2A1NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488323 | 0.84 | KIF11 (0.35) | CD274SLC2A1NPBWR1KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125701-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-03 | — | — | EP | claimed |
| EP-0125701-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | claimed |
| US-4803226-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4803221-A | Anthracene derivatives | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0125701-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-03 | — | — | EP | disclosed |
| US-4719047-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0125701-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |