SCHEMBL10488258

SCHEMBL10488258

CCOc1c2ccccc2c(C=O)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
SLC2A1 P11166 2/20 0.43
PADI4 Q9UM07 1/20 0.42
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
MAPT P10636 4/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
PTGER4 P35408 2/20 0.38
CYP1A2 P05177 2/20 0.38
MCL1 Q07820 2/20 0.38
CYP2D6 P10635 1/20 0.38
SQSTM1 Q13501 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10551445 0.91 PADI4 (0.46) GAAL3MBTL1TDP1SLC2A1PADI4
SCHEMBL12012551 0.90 GAA (0.45) GAAL3MBTL1TDP1SLC2A1PADI4
SCHEMBL1040193 0.84 L3MBTL1 (0.59) GAAL3MBTL1TDP1SLC2A1PADI4
SCHEMBL51657 0.83 ALDH1A1 (0.50) L3MBTL1SLC2A1MAPTALDH1A1SMN1; SMN2
SCHEMBL29366895 0.83 ALDH1A1 (0.50) L3MBTL1SLC2A1MAPTALDH1A1SMN1; SMN2
SCHEMBL10488312 0.80 L3MBTL1 (0.41) GAAL3MBTL1TDP1PADI4ADRB2
SCHEMBL17189612 0.80 FFAR1 (0.40) GAAL3MBTL1TDP1PADI4ADRB2
SCHEMBL9466155 0.79 GAA (0.39) GAAL3MBTL1TDP1PADI4ADRB2
SCHEMBL10488272 0.78 PADI4 (0.44) GAAL3MBTL1TDP1PADI4ADRB2
SCHEMBL10488238 0.78 ALDH1A1 (0.65) SLC2A1PADI4MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9779862-B2 Magnetic substance and magnetic substance manufacturing method IHI CORPORATION (JP) 2017-10-03 US disclosed
US-9779862-B2 Magnetic substance and magnetic substance manufacturing method IHI CORPORATION (JP) 2017-10-03 US disclosed
US-20150318095-A1 MAGNETIC SUBSTANCE AND MAGNETIC SUBSTANCE MANUFACTURING METHOD IHI CORPORATION (JP) 2015-11-05 US disclosed
US-20150318095-A1 MAGNETIC SUBSTANCE AND MAGNETIC SUBSTANCE MANUFACTURING METHOD IHI CORPORATION (JP) 2015-11-05 US disclosed
EP-2933802-A1 MAGNETIC BODY, AND METHOD FOR MANUFACTURING MAGNETIC BODY IHI Corporation (JP) 2015-10-21 EP disclosed
US-4803226-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1989-02-07 US disclosed
US-4803221-A Anthracene derivatives BURROUGHS WELLCOME CO. (US) 1989-02-07 US disclosed
US-4719047-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
US-4719049-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
EP-0125702-B1 POLYCYCLIC AROMATIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1987-08-12 EP disclosed
EP-0125702-A2 Polycyclic aromatic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1984-11-21 EP disclosed