Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488217 | 0.93 | SLC2A1 (0.36) | SLC2A1CYP1A2CD274HTTKDM4E | |
| Hydrochloric Acid SCHEMBL10488317 | 0.92 | HTT (0.38) | SLC2A1CYP1A2CD274HTTKDM4E | |
| SCHEMBL10488305 | 0.88 | SLC2A1 (0.36) | SLC2A1 | |
| SCHEMBL10488653 | 0.85 | SLC2A1 (0.50) | SLC2A1CYP1A2CD274KDM4ESMN1; SMN2 | |
| SCHEMBL10488878 | 0.83 | SLC2A1 (0.46) | SLC2A1CYP1A2CD274KDM4E | |
| SCHEMBL10488369 | 0.83 | SLC2A1 (0.46) | SLC2A1CYP1A2CD274HSD17B10 | |
| SCHEMBL10488276 | 0.82 | SLC2A1 (0.46) | SLC2A1CYP1A2CD274 | |
| Hydrochloric Acid SCHEMBL10488338 | 0.82 | SLC2A1 (0.45) | SLC2A1CYP1A2CD274 | |
| SCHEMBL10488327 | 0.79 | SLC2A1 (0.35) | SLC2A1CYP1A2CD274RIPK1 | |
| Hydrochloric Acid SCHEMBL10488518 | 0.78 | SLC2A1 (0.34) | SLC2A1CYP1A2CD274HTTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803221-A | Anthracene derivatives | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |