Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891817 | 0.89 | PADI4 (0.50) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| SCHEMBL150623 | 0.81 | ALDH1A1 (0.64) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29429129 | 0.81 | ALDH1A1 (0.64) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL986883 | 0.81 | PADI4 (0.64) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| SCHEMBL29588097 | 0.81 | PADI4 (0.64) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9397561 | 0.78 | PADI4 (0.61) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| Bromide SCHEMBL11303999 | 0.78 | PADI4 (0.61) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| Iodide SCHEMBL9460922 | 0.78 | PADI4 (0.61) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| SCHEMBL6155635 | 0.77 | PADI4 (0.36) | KDM4EALDH1A1PADI4MEN1KMT2A | |
| SCHEMBL14823441 | 0.76 | CA1 (0.51) | KDM4EALDH1A1PADI4MAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9285320-B2 | Fluorescent cytotoxic compounds specific for the cellular polyamine transport system | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20130337494-A1 | FLUORESCENT CYTOTOXIC COMPOUNDS SPECIFIC FOR THE CELLULAR POLYAMINE TRANSPORT SYSTEM | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-12-19 | — | — | US | disclosed |
| US-8410311-B1 | Fluorescent cytotoxic compounds specific for the cellular polyamine transport system | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-4803226-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4803221-A | Anthracene derivatives | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4719047-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0125702-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-08-12 | — | — | EP | disclosed |
| EP-0125702-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |