Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805248 | 0.83 | ALDH1A1 (0.43) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9808407 | 0.81 | MPL (0.40) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10488397 | 0.81 | MPL (0.40) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11397305 | 0.79 | CYP3A4 (0.40) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10488378 | 0.77 | L3MBTL1 (0.41) | MPLALDH1A1KMT2AMAPTGAA | |
| SCHEMBL8959215 | 0.76 | ALDH1A1 (0.42) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7814626 | 0.75 | MAPT (0.54) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10631047 | 0.75 | ALDH1A1 (0.39) | MPLALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL246828 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL11327329 | 0.74 | MYC (0.41) | MPLALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179549-B1 | WATER-SOLUBLE DYE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-23 | — | — | EP | disclosed |
| US-4799960-A | JET PRINTING; METALLIZED AZO DYES; WORKABILITY IN LIQUID MEDIUM | CANON KABUSHIKI KAISHA (JP) | 1989-01-24 | — | — | US | disclosed |
| US-4705528-A | Water-soluble triazine black dyes from cellulose reactive groups and suitable for use in inks | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-10 | — | — | US | disclosed |
| EP-0179549-A2 | Water-soluble dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-04-30 | — | — | EP | disclosed |