SCHEMBL10488478

SCHEMBL10488478

CC(C)(C)C(C(=O)c1ccccc1)C(=O)c1ccccc1.CCCCc1ccccc1C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 3/20 0.38
CTSG P08311 3/20 0.38
CTRB1 P17538 3/20 0.38
CMA1 P23946 3/20 0.38
ELANE P08246 1/20 0.37
CTRC Q99895 1/20 0.37
TRPV1 Q8NER1 1/20 0.36
CYSLTR2 Q9NS75 3/20 0.36
CYSLTR1 Q9Y271 3/20 0.36
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
PGR P06401 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131361 0.82 TSHR (0.46) ALDH1A1LMNA
SCHEMBL298005 0.77 LIPG (0.53) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL11422882 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL2125103 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL2123855 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL1577630 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL5709997 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL5164407 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
SCHEMBL11441324 0.76 LIPG (0.56) CYSLTR2CYSLTR1ALDH1A1LMNA
Acetophenone SCHEMBL10488608 0.75 SMN1; SMN2 (0.48) CES2CES1ALDH1A1LMNAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4814162-A SUNSCREENS L'OREAL (FR) 1989-03-21 US disclosed