Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418270 | 0.92 | TDP1 (0.50) | MAPTALDH1A1LMNATDP1L3MBTL1 | |
| Methyl Alcohol SCHEMBL27531298 | 0.90 | TDP1 (0.48) | MAPTALDH1A1LMNATDP1L3MBTL1 | |
| Acetophenone SCHEMBL12475371 | 0.85 | MAPT (0.48) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL10789264 | 0.81 | TDP1 (0.45) | MAPTALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL324099 | 0.79 | CES2 (0.61) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| Acetophenone SCHEMBL30537005 | 0.78 | — | — | |
| Acetophenone SCHEMBL30537000 | 0.78 | — | — | |
| Acetophenone SCHEMBL737 | 0.78 | — | — | |
| Acetophenone SCHEMBL16745259 | 0.78 | — | — | |
| Acetophenone SCHEMBL1450855 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814162-A | SUNSCREENS | L'OREAL (FR) | 1989-03-21 | — | — | US | disclosed |