Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488910 | 0.90 | PDGFRB (0.42) | ALDH1A1HPGDLMNAMAPTGAA | |
| SCHEMBL10488556 | 0.86 | KMT2A (0.59) | ALDH1A1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10488475 | 0.84 | POLB (0.55) | RAB9AALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL10488476 | 0.81 | LRRK2 (0.50) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL10488504 | 0.81 | KMT2A (0.57) | RAB9AALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL10488935 | 0.79 | EGFR (0.54) | RAB9ASMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL10515210 | 0.78 | MAPT (0.46) | SMN1; SMN2HPGDLMNAMAPTKMT2A | |
| SCHEMBL10488603 | 0.74 | POLB (0.55) | ALDH1A1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10488575 | 0.74 | FTO (0.44) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10488751 | 0.74 | PTGS2 (0.45) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871737-A | 3-Amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-10-03 | — | — | US | disclosed |
| US-4826866-A | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-02 | — | — | US | disclosed |