Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488880 | 0.89 | SLC2A1 (0.38) | SLC2A1CD274CYP1A2NPBWR1KMT2A | |
| SCHEMBL10488281 | 0.88 | SLC2A1 (0.37) | SLC2A1CD274NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488305 | 0.87 | SLC2A1 (0.36) | SLC2A1 | |
| SCHEMBL10488653 | 0.87 | SLC2A1 (0.50) | SLC2A1CD274PDCD1CYP1A2TP53 | |
| SCHEMBL10488335 | 0.83 | SLC2A1 (0.36) | SLC2A1CD274PDCD1CYP1A2TP53 | |
| SCHEMBL10484383 | 0.83 | SLC2A1 (0.40) | SLC2A1CYP1A2HIF1ANPBWR1KMT2A | |
| SCHEMBL10348691 | 0.82 | SLC2A1 (0.39) | SLC2A1CD274CYP1A2CYP2D6HIF1A | |
| SCHEMBL10488852 | 0.82 | CD274 (0.42) | SLC2A1CD274PDCD1CYP1A2TP53 | |
| SCHEMBL10349038 | 0.82 | SLC2A1 (0.38) | SLC2A1CD274CYP2D6NPBWR1KMT2A | |
| SCHEMBL10492815 | 0.82 | SLC2A1 (0.42) | SLC2A1CYP1A2NPBWR1KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803221-A | Anthracene derivatives | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |