SCHEMBL10488281

SCHEMBL10488281

CC(CO)(COS(C)(=O)=O)NCc1c2ccccc2c(CCCl)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 5/20 0.37
NPBWR1 P48145 1/20 0.31
KMT2A Q03164 1/20 0.31
MCHR1 Q99705 1/20 0.31
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10488880 0.89 SLC2A1 (0.38) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10488657 0.88 SLC2A1 (0.40) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10488276 0.87 SLC2A1 (0.46) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10488305 0.85 SLC2A1 (0.36) SLC2A1
SCHEMBL10488335 0.84 SLC2A1 (0.36) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10488212 0.83 CYP1A2 (0.37) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10349038 0.82 SLC2A1 (0.38) SLC2A1NPBWR1KMT2AMCHR1CD274
Hydrochloric Acid SCHEMBL10488854 0.82 NPBWR1 (0.37) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10488353 0.82 SLC2A1 (0.37) SLC2A1NPBWR1KMT2AMCHR1CD274
SCHEMBL10484383 0.81 SLC2A1 (0.40) SLC2A1NPBWR1KMT2AMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4803221-A Anthracene derivatives BURROUGHS WELLCOME CO. (US) 1989-02-07 US disclosed
US-4719049-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed