Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | MYLK | Q15746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488353 | 0.93 | SLC2A1 (0.37) | SLC2A1KMT2AMEN1CD274NPBWR1 | |
| SCHEMBL10488332 | 0.88 | SLC2A1 (0.44) | SLC2A1CYP3A4CYP1A2CYP2C19TP53 | |
| SCHEMBL10488880 | 0.87 | SLC2A1 (0.38) | SLC2A1CYP1A2KMT2ACD274NPBWR1 | |
| SCHEMBL10488851 | 0.84 | CD274 (0.37) | SLC2A1CYP3A4CYP1A2CYP2C19TP53 | |
| SCHEMBL10488281 | 0.84 | SLC2A1 (0.37) | SLC2A1KMT2ACD274NPBWR1MCHR1 | |
| SCHEMBL10488657 | 0.83 | SLC2A1 (0.40) | SLC2A1CYP3A4CYP1A2TP53KMT2A | |
| Hydrochloric Acid SCHEMBL10488311 | 0.83 | CD274 (0.36) | SLC2A1CYP3A4CYP1A2TP53KMT2A | |
| SCHEMBL10349038 | 0.83 | SLC2A1 (0.38) | SLC2A1KMT2ACD274CYP2D6NPBWR1 | |
| SCHEMBL10692661 | 0.82 | MCL1 (0.33) | SLC2A1CD274 | |
| SCHEMBL10488350 | 0.81 | SLC2A1 (0.45) | SLC2A1CYP3A4CYP1A2CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803221-A | Anthracene derivatives | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |