Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.67 |
| ▸ | GNB1 | P62873 | 5/20 | 0.67 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.62 |
| ▸ | HPGDS | O60760 | 1/20 | 0.62 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | CHAT | P28329 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136833 | 0.88 | GNG2 (0.62) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL10488916 | 0.87 | PHLPP2 (0.67) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL17082608 | 0.86 | GNG2 (0.74) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL13214010 | 0.86 | GNG2 (0.78) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL3019527 | 0.85 | GNG2 (0.77) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL8779914 | 0.85 | GNG2 (0.81) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL3019530 | 0.85 | GNG2 (0.77) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL13021512 | 0.84 | GNG2 (0.92) | GNG2GNB1P2RY4PHLPP2CYP1A2 | |
| SCHEMBL6876404 | 0.83 | GNG2 (0.78) | GNG2GNB1P2RY4HPGDSPHLPP2 | |
| SCHEMBL10768456 | 0.83 | PHLPP2 (0.64) | GNG2GNB1P2RY4HPGDSPHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864018-A | REACTIVE TRIAZINE-TYPE DYES HAVING PREFERENTIAL BINDING CAPACITY FOR BIOLOGICAL MOLECULES; PROTEIN AND ENZYMES ADSORBENTS AND PRECIPITATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-05 | — | — | US | disclosed |
| EP-0209284-A2 | Anthraquinone derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-21 | — | — | EP | disclosed |