SCHEMBL6876404

SCHEMBL6876404

Nc1ccc(Nc2cc(S(=O)(=O)O)c(N)c3c2C(=O)c2ccccc2C3=O)cc1S(=O)(=O)O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 5/20 0.78
GNB1 P62873 5/20 0.78
P2RY12 Q9H244 7/20 0.73
P2RY4 P51582 5/20 0.71
PHLPP2 Q6ZVD8 2/20 0.70
CYP1A2 P05177 2/20 0.70
CYP2C9 P11712 2/20 0.70
ALOX15 P16050 2/20 0.70
HSD17B10 Q99714 2/20 0.70
ALDH1A1 P00352 1/20 0.70
CYP3A4 P08684 1/20 0.70
HPGD P15428 1/20 0.70
MAPK1 P28482 1/20 0.70
CYP2C19 P33261 1/20 0.70
HIF1A Q16665 1/20 0.70
HPGDS O60760 1/20 0.64
CHAT P28329 2/20 0.62
P2RY2 P41231 4/20 0.61
P2RY6 Q15077 3/20 0.61
ENTPD1 P49961 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3026737 0.99 GNG2 (0.76) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL3026734 0.99 GNG2 (0.76) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL13021512 0.91 GNG2 (0.92) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL8645343 0.91 GNG2 (0.65) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL4650171 0.90 GNG2 (0.78) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL11423174 0.90 GNG2 (0.73) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL6879091 0.89 GNG2 (0.61) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL8642068 0.89 GNG2 (0.61) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL17082608 0.88 GNG2 (0.74) GNG2GNB1P2RY12P2RY4PHLPP2
SCHEMBL13214010 0.88 GNG2 (0.78) GNG2GNB1P2RY12P2RY4PHLPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3613486-B1 METHOD AND INSTALLATION FOR THE PURIFICATION OF EPO AND/OR AN EPO DERIVATIVE UGA BIOPHARMA GMBH (DE) 2020-10-07 EP claimed
EP-3613486-A1 METHOD AND INSTALLATION FOR THE PURIFICATION OF EPO AND/OR AN EPO DERIVATIVE UGA Biopharma GmbH (DE) 2020-02-26 EP claimed
EP-0099859-B1 PROCESS FOR DYEING DIFFERENTIAL-DYEING FIBRES CIBA-GEIGY AG (CH) 1987-04-01 EP claimed
EP-3613486-B1 METHOD AND INSTALLATION FOR THE PURIFICATION OF EPO AND/OR AN EPO DERIVATIVE UGA BIOPHARMA GMBH (DE) 2020-10-07 EP disclosed
EP-3102637-B1 METHOD FOR PURIFICATION OF ANTIBODIES, ANTIBODY FRAGMENTS OR ENGINEERED VARIANTS THEREOF USING SPECIFIC ANTHRAQUINONE DYE-LIGAND STRUCTURES BASF SE (DE) 2018-04-11 EP disclosed
EP-2129653-B1 NOVEL P2Y12 RECEPTOR ANTAGONISTS Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2017-05-17 EP disclosed
US-20160347789-A1 Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures BASF SE (DE) 2016-12-01 US disclosed
US-20160347789-A1 Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures BASF SE (DE) 2016-12-01 US disclosed
US-8227599-B2 Adsorbents comprising anthraquinone dye-ligends for the separation of biological materials BASF SE (DE) 2012-07-24 US disclosed
US-8227599-B2 Adsorbents comprising anthraquinone dye-ligends for the separation of biological materials BASF SE (DE) 2012-07-24 US disclosed
EP-1866379-B1 ADSORBENTS COMPRISING ANTHRAQUINONE DYE-LIGANDS FOR THE SEPARATION OF BIOLOGICAL MATERIALS BASF SE (DE) 2011-05-18 EP disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
US-4294580-A HYDROXYL OR NITROGEN, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-10-13 US disclosed
US-4255325-A AZO, ANTHRAQUINONE, FORMAZANE, AND PHTHALOCYANINE DYES; COLOR AND WASHFASTNESS; AMINO HALO TRIAZINE CARBAZIDE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
WO-1981000111-A1 MONO-AZO REACTANTS FOR FIBERS,PRODUCTION PROCESS THEREOF AND UTILIZATION THEREOF SANDOZ AG (CH) 1981-01-22 WO disclosed
US-4242259-A TRIAZINE DYES, COTTON BAYER AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
EP-0013765-A1 Reactive azodyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups BAYER AG (DE) 1980-08-06 EP disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-3947407-A ANTHRAQUINONE DYE CIBA-GEIGY AG (CH) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160347789-A1 Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures ANTXR2, FCGR3B, IGLV6-57 GNG2 215/4885GNB1 305/4885P2RY12 4455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.