Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459627 | 0.90 | ALDH1A1 (0.58) | TSHRPBRM1ALDH1A1CES2CES1 | |
| SCHEMBL27858886 | 0.86 | ALDH1A1 (0.53) | TSHRPBRM1ALDH1A1KDM4ECES2 | |
| SCHEMBL28338341 | 0.85 | PBRM1 (0.53) | TSHRPBRM1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27459628 | 0.84 | ALDH1A1 (0.51) | TSHRPBRM1ALDH1A1CES2CES1 | |
| SCHEMBL31356504 | 0.84 | TSHR (0.65) | TSHRPBRM1ALDH1A1DPP4KDM4E | |
| SCHEMBL275485 | 0.84 | TSHR (0.65) | TSHRPBRM1ALDH1A1DPP4KDM4E | |
| SCHEMBL28702990 | 0.82 | TSHR (0.63) | TSHRPBRM1ALDH1A1DPP4KDM4E | |
| SCHEMBL617135 | 0.82 | ALDH1A1 (0.48) | TSHRPBRM1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7778738 | 0.82 | TSHR (0.63) | TSHRPBRM1ALDH1A1DPP4KDM4E | |
| SCHEMBL9725353 | 0.82 | TSHR (0.57) | TSHRPBRM1ALDH1A1DPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885278-A | 5-substituted 10-cyanomethylenethieno(3,4-B)benzazepines | BASF AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |