SCHEMBL28338341

SCHEMBL28338341

COC(=O)c1cccc(Cl)c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.53
NR4A2 P43354 2/20 0.50
ALDH1A1 P00352 4/20 0.49
HSD17B10 Q99714 2/20 0.49
KDM4E B2RXH2 2/20 0.49
TSHR P16473 2/20 0.48
LMNA P02545 2/20 0.47
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CFTR P13569 1/20 0.46
POLB P06746 3/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MAPT P10636 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Phthalate SCHEMBL28522663 0.92 PBRM1 (0.56) PBRM1NR4A2ALDH1A1HSD17B10KDM4E
SCHEMBL29445387 0.89 CA12 (0.53) PBRM1NR4A2ALDH1A1HSD17B10KDM4E
SCHEMBL7671969 0.89 CA12 (0.53) PBRM1NR4A2ALDH1A1HSD17B10KDM4E
SCHEMBL8669430 0.87 TSHR (0.55) ALDH1A1HSD17B10KDM4ETSHRLMNA
SCHEMBL10488994 0.85 TSHR (0.52) PBRM1ALDH1A1HSD17B10KDM4ETSHR
SCHEMBL4627944 0.85 CA12 (0.53) PBRM1NR4A2ALDH1A1HSD17B10KDM4E
SCHEMBL1666447 0.83 TSHR (0.52) ALDH1A1HSD17B10KDM4ETSHRLMNA
SCHEMBL275485 0.81 TSHR (0.65) PBRM1ALDH1A1HSD17B10KDM4ETSHR
SCHEMBL31356504 0.81 TSHR (0.65) PBRM1ALDH1A1HSD17B10KDM4ETSHR
SCHEMBL517538 0.81 CA12 (0.61) NR4A2ALDH1A1HSD17B10KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330104-A Pretreatment purifying tube special for quantitative analysis of tobacco pesticide residues and high-throughput detection method of tobacco pesticide residues 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 2024-07-12 CN claimed
CN-116514750-A Production process of 2, 3',4' -biphenyl tetracarboxylic dianhydride 安徽秀朗新材料科技有限公司 2023-08-01 CN claimed
CN-110461158-B Herbicidal mixtures comprising 2- [ (2, 4-dichlorophenyl) methyl ] -4, 4-dimethyl-3-isoxazolidone, topramezone and mefenpyr 拜耳公司 2021-12-10 CN claimed
CN-110643039-A Polyimide precursor composition and preparation method thereof 合肥中聚合臣电子材料有限公司 2020-01-03 CN claimed
CN-119997813-A Emulsifiable concentrate with lactone-based solvent system 巴斯夫欧洲公司 2025-05-13 CN disclosed
CN-115003656-B [ (1, 4, 5-Trisubstituted 1H-pyrazol-3-yl) sulfanyl ] acetic acid derivatives and salts thereof and their use as active herbicidal ingredients 拜耳公司 2025-03-04 CN disclosed
CN-114728915-B [ (1, 5-Diphenyl-1H-1, 2, 4-triazol-3-yl) oxy ] acetic acid derivatives and salts thereof, crop protection compositions containing same, method for producing same, and use thereof as safeners 拜耳公司 2024-08-30 CN disclosed
CN-118368978-A Pesticide composition and method for producing same 三井化学植保株式会社 2024-07-19 CN disclosed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN disclosed
CN-116514750-A Production process of 2, 3',4' -biphenyl tetracarboxylic dianhydride 安徽秀朗新材料科技有限公司 2023-08-01 CN disclosed
CN-115915942-A Selective herbicides based on substituted isoxazoline carboxamides and mefenpyr-diethyl 拜耳公司 2023-04-04 CN disclosed
CN-115702157-A Substituted pyrrolin-2-ones and their use as herbicides 拜耳公司 2023-02-14 CN disclosed
CN-111836802-A Fungicidal acibenzoates 拜耳公司 2020-10-27 CN disclosed
CN-111770685-A Fatty acid derivatives as herbicides 科莱恩国际有限公司 2020-10-13 CN disclosed
CN-108777966-B Granular pesticide composition and preparation method thereof 组合化学工业株式会社 2020-06-30 CN disclosed
CN-111093375-A Novel isothiazolo structure-based bicyclic rings, process for their preparation and their use as herbicides and/or plant growth regulators 拜耳作物科学股份公司 2020-05-01 CN disclosed
CN-110650628-A Trisubstituted silylheteroaryloxyquinolines and analogs thereof 拜耳公司 2020-01-03 CN disclosed
CN-110643039-A Polyimide precursor composition and preparation method thereof 合肥中聚合臣电子材料有限公司 2020-01-03 CN disclosed
CN-110582484-A Trisubstituted silylmethylphenoxyquinolines and analogs thereof 拜耳公司 2019-12-17 CN disclosed
CN-105330634-A One-pot method for preparing 3-hydroxyphtalic anhydride JINAN XUANHONG BIOLOG PHARMACEUTICAL CO LTD 2016-02-17 CN disclosed