Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553031 | 0.98 | ACHE (0.51) | ACHEBACE1NFKB1NFKB2RELA | |
| SCHEMBL28570427 | 0.94 | ACHE (0.46) | ACHEBACE1NFKB1NFKB2RELA | |
| SCHEMBL28549550 | 0.86 | ACHE (0.40) | ACHEBACE1ERBB2MEN1ALDH1A1 | |
| SCHEMBL2880968 | 0.84 | ACHE (0.37) | ACHEBACE1PTGS2PTGS1MGLL | |
| SCHEMBL6267394 | 0.84 | ACHE (0.47) | ACHEBACE1NFKB1NFKB2RELA | |
| SCHEMBL21819284 | 0.82 | ACHE (0.40) | ACHEBACE1PTGS2PTGS1MGLL | |
| SCHEMBL11666302 | 0.78 | ELANE (0.36) | ACHEBACE1ERBB2MEN1MAPT | |
| SCHEMBL28562469 | 0.78 | ACHE (0.38) | ACHEBACE1ERBB2MEN1ALDH1A1 | |
| SCHEMBL28247119 | 0.78 | ACHE (0.44) | ACHEBACE1NFKB1NFKB2RELA | |
| SCHEMBL6274683 | 0.76 | MEN1 (0.41) | ACHEBACE1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886880-A | Process for the preparation of triphendioxazines | CIBA-GEIGY CORPORATION (US) | 1989-12-12 | — | — | US | claimed |
| CN-112739725-B | Amino quinone anti-polymerization agent and method of use thereof | 埃科莱布美国股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-112739725-A | Amino quinone anti-polymerization agents and methods of use thereof | 埃科莱布美国股份有限公司 | 2021-04-30 | — | — | CN | disclosed |
| US-4886880-A | Process for the preparation of triphendioxazines | CIBA-GEIGY CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |
| US-4886880-A | Process for the preparation of triphendioxazines | CIBA-GEIGY CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |
| US-4845213-A | Process for preparing triphendioxazine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |