Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247119 | 0.95 | ACHE (0.44) | ACHEBACE1GPR84MAPTNFKB1 | |
| SCHEMBL10489063 | 0.84 | ACHE (0.49) | ACHEBACE1GPR84DNM1MAPT | |
| SCHEMBL28553031 | 0.82 | ACHE (0.51) | ACHEBACE1GPR84DNM1MAPT | |
| SCHEMBL28570427 | 0.78 | ACHE (0.46) | ACHEBACE1MAPTNFKB1NFKB2 | |
| SCHEMBL6274683 | 0.74 | MEN1 (0.41) | ACHEBACE1 | |
| SCHEMBL28549550 | 0.73 | ACHE (0.40) | ACHEBACE1MAPTDAOERBB2 | |
| SCHEMBL28562469 | 0.69 | ACHE (0.38) | ACHEBACE1MAPTERBB2 | |
| Benzoquinone SCHEMBL11072887 | 0.68 | ACHE (0.54) | ACHEBACE1GPR84NFKB1NFKB2 | |
| SCHEMBL2880968 | 0.67 | ACHE (0.37) | ACHEBACE1GPR84DNM1MAPT | |
| SCHEMBL21819284 | 0.66 | ACHE (0.40) | ACHEBACE1GPR84DNM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005115145-A2 | QUINONE SUBSTITUTED QUINAZOLINE AND QUINOLINE KINASE INHIBITORS | WYETH (US) | 2005-12-08 | — | — | WO | claimed |