Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489480 | 1.00 | TAS1R3 (0.40) | TAS1R3TAS1R1TAS1R2NPC1RAB9A | |
| SCHEMBL29977959 | 0.83 | PARP1 (0.43) | TAS1R3TAS1R1TAS1R2NPC1ALDH1A1 | |
| SCHEMBL11596060 | 0.78 | KMT2A (0.58) | TAS1R3TAS1R1TAS1R2KMT2AALDH1A1 | |
| SCHEMBL9860570 | 0.77 | CYP2D6 (0.45) | TAS1R3TAS1R1TAS1R2NPC1RAB9A | |
| SCHEMBL8125269 | 0.77 | HTR2C (0.46) | TAS1R3TAS1R1TAS1R2NPC1RAB9A | |
| SCHEMBL2858367 | 0.76 | MEN1 (0.40) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL31037558 | 0.76 | MEN1 (0.40) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL27100577 | 0.75 | KMT2A (0.41) | TAS1R3TAS1R1TAS1R2KMT2AALDH1A1 | |
| SCHEMBL8370175 | 0.75 | LMNA (0.36) | TAS1R3TAS1R1TAS1R2KMT2AALOX12 | |
| SCHEMBL9050537 | 0.74 | KMT2A (0.62) | TAS1R3TAS1R1TAS1R2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868337-A | Optically active borinic esters and ketones | ALDRICH-BORANES, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4795821-A | Optically active borinic esters and ketones | ALDRICH-BORANES, INC. (US) | 1989-01-03 | — | — | US | disclosed |