Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | BID | P55957 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 4/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 2/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 4/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489696 | 0.92 | PPARA (0.56) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489767 | 0.90 | PPARA (0.61) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489739 | 0.89 | CLCN2 (0.45) | PPARAPLK1LPAR2LPAR3KDM4E | |
| SCHEMBL10489676 | 0.89 | PPARA (0.64) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489716 | 0.89 | ALDH1A1 (0.52) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489826 | 0.87 | HPGD (0.46) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489704 | 0.86 | TRPV1 (0.45) | PPARAPPARGKDM4EMAPT | |
| SCHEMBL10489790 | 0.85 | SMN1; SMN2 (0.54) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489657 | 0.84 | SMN1; SMN2 (0.50) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL10489761 | 0.84 | NPC1 (0.58) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | claimed |
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |