Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489667 | 0.92 | PPARA (0.49) | TRPV1RAB9ANPC1NPSR1FAAH | |
| SCHEMBL10489802 | 0.91 | PPARA (0.54) | FAAHMAPTPPARAKDM4EPPARG | |
| SCHEMBL10489876 | 0.91 | RAB9A (0.50) | TRPV1RAB9ANPC1NPSR1FAAH | |
| SCHEMBL10489875 | 0.90 | PPARA (0.56) | FAAHMAPTPPARAKDM4EPPARG | |
| SCHEMBL10489730 | 0.86 | PPARA (0.48) | MAPTPPARAKDM4EPPARG | |
| SCHEMBL10489716 | 0.84 | ALDH1A1 (0.52) | RAB9ANPC1KMT2AALDH1A1MAPT | |
| SCHEMBL10489709 | 0.83 | ALDH1A1 (0.45) | TRPV1RAB9ANPC1NPSR1KMT2A | |
| SCHEMBL10489826 | 0.83 | HPGD (0.46) | KMT2AALDH1A1MEN1HPGDCYP1A2 | |
| SCHEMBL10489761 | 0.82 | NPC1 (0.58) | RAB9ANPC1KMT2AALDH1A1MAPT | |
| SCHEMBL10489904 | 0.82 | RAB9A (0.60) | TRPV1RAB9ANPC1FAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |