Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489747 | 0.94 | NPC1 (0.60) | NPC1RAB9AMAPK1GFERAKR1C3 | |
| SCHEMBL11594657 | 0.84 | NPC1 (0.66) | NPC1RAB9AHDAC8TP53ALOX15 | |
| SCHEMBL14363181 | 0.84 | NPC1 (0.66) | NPC1RAB9AHDAC8TP53ALOX15 | |
| SCHEMBL13964389 | 0.84 | F10 (0.55) | NPC1RAB9AMAPK1GFERTP53 | |
| SCHEMBL5222453 | 0.83 | RAF1 (0.60) | NPC1RAB9AMAPK1HDAC8TP53 | |
| SCHEMBL12189549 | 0.82 | NPC1 (0.72) | NPC1RAB9AMAPK1GFERMEN1 | |
| SCHEMBL17122454 | 0.82 | ALDH1A1 (0.58) | NPC1RAB9AMAPK1GFERTP53 | |
| SCHEMBL16366881 | 0.81 | MAPK1 (0.56) | NPC1RAB9AMAPK1GFERAKR1C3 | |
| SCHEMBL12700350 | 0.81 | ALDH1A1 (0.58) | NPC1RAB9AMAPK1GFERTP53 | |
| SCHEMBL12700355 | 0.81 | MEN1 (0.60) | NPC1RAB9ATP53ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857305-A | N-phenylphthalisoimides as ultraviolet radiation absorbers | STEPAN COMPANY (US) | 1989-08-15 | — | — | US | disclosed |
| US-4788054-A | SUNSCREEN AGENTS FOR PLASTICS, SKINS, FIBERS, COATINGS | STEPAN COMPANY (US) | 1988-11-29 | — | — | US | disclosed |