Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | PLG | P00747 | 3/20 | 0.64 |
| ▸ | KLK1 | P06870 | 2/20 | 0.64 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.64 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | PLAU | P00749 | 1/20 | 0.63 |
| ▸ | PLAT | P00750 | 1/20 | 0.63 |
| ▸ | PNLIP | P16233 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363181 | 0.88 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL2272830 | 0.87 | KLKB1 (0.69) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL10489747 | 0.84 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL10489750 | 0.84 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL5383984 | 0.84 | KLKB1 (0.66) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL12521437 | 0.84 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL14514566 | 0.81 | PLG (0.67) | NPC1RAB9AMEN1KMT2APLG | |
| SCHEMBL5222453 | 0.81 | RAF1 (0.60) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL5080078 | 0.80 | PNLIP (0.91) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL2048865 | 0.79 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072753-A | DERMATITIS, MULTIPLE SCLEROSIS, BENZANILIDES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4032635-A | BENZANILIDE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-06-28 | — | — | US | disclosed |