Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminobenzoic Acid SCHEMBL7653067 | 1.00 | TP53 (0.46) | TP53TSHRKMT2ANPC1RAB9A | |
| Terephthalic Acid SCHEMBL855281 | 0.90 | TSHR (0.57) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL10938231 | 0.90 | TSHR (0.57) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28791012 | 0.90 | TSHR (0.57) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Aminobenzoic Acid SCHEMBL269053 | 0.86 | TSHR (0.48) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL11809850 | 0.86 | TSHR (0.52) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL29132843 | 0.86 | TSHR (0.52) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL27843678 | 0.86 | TSHR (0.52) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Aminobenzoic Acid SCHEMBL5875286 | 0.86 | TSHR (0.52) | TP53TSHRKMT2ANPC1RAB9A | |
| Aminobenzoic Acid SCHEMBL10420842 | 0.86 | TSHR (0.52) | TP53TSHRKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740528-B1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX THERAPEUTICS INC (US) | 2003-03-26 | — | — | EP | claimed |
| EP-0740528-A4 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP (US) | 1998-04-01 | — | — | EP | claimed |
| US-5733572-A | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles | IMARX PHARMACEUTICAL CORP. (US) | 1998-03-31 | — | — | US | claimed |
| EP-0740528-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1996-11-06 | — | — | EP | claimed |
| WO-1995015118-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1995-06-08 | — | — | WO | claimed |
| CN-111699217-B | Polyurethane resin composition | 三悠瑞克株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-111699217-A | Polyurethane resin composition | 三悠瑞克株式会社 | 2020-09-22 | — | — | CN | disclosed |
| CN-106167552-B | Grinding pad and its manufacture method | FNS科技有限公司 | 2018-01-02 | — | — | CN | disclosed |
| US-20110004150-A1 | Transdermal Delivery Using Encapsulated Agent Activated by Ultrasound and or Heat | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2011-01-06 | — | — | US | disclosed |
| US-7232431-B1 | Intradermal incorporation of microparticles containing encapsulated drugs using low frequency ultrasound | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2007-06-19 | — | — | US | disclosed |
| US-20060034904-A1 | Transdermal delivery using emcapsulated agent activated by ultrasound and or heat | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2006-02-16 | — | — | US | disclosed |
| US-20060008483-A1 | Dispersions of lipids for use as therapeutic and cosmetic agents and intracellular delivery vehicles | BIOTECH TOOLS SA (BE) | 2006-01-12 | — | — | US | disclosed |
| US-20020138037-A1 | Method and apparatus for intradermal incorporation of microparticles containing encapsulated drugs using low frequency ultrasound | ULTRA-SONIC TECHNOLOGIES, L.L.C. | 2002-09-26 | — | — | US | disclosed |
| US-6414139-B1 | MIXTURE WITH GAS OR GAS PRECURSOR; DIAGNOSTIC IMAGING; ULTRASOUND AND COMPUTER AXIAL TOMOGRAPHY | IMARX THERAPEUTICS, INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0740528-A4 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5733572-A | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles | IMARX PHARMACEUTICAL CORP. (US) | 1998-03-31 | — | — | US | disclosed |
| WO-1998009600-A2 | NOVEL SILICON AMPHIPHILIC COMPOUNDS AND THE USE THEREOF | IMARX PHARMACEUTICAL CORP. (US) | 1998-03-12 | — | — | WO | disclosed |
| CN-1137748-A | Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor | IMARX PHARMACEUTICAL CORP (US) | 1996-12-11 | — | — | CN | disclosed |
| EP-0740528-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995015118-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1995-06-08 | — | — | WO | disclosed |