Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminobenzoic Acid SCHEMBL1049003 | 1.00 | TP53 (0.46) | TP53TSHRKMT2ANPC1RAB9A | |
| Terephthalic Acid SCHEMBL855281 | 0.90 | TSHR (0.57) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL10938231 | 0.90 | TSHR (0.57) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28791012 | 0.90 | TSHR (0.57) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Aminobenzoic Acid SCHEMBL269053 | 0.86 | TSHR (0.48) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL11809850 | 0.86 | TSHR (0.52) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL29132843 | 0.86 | TSHR (0.52) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL27843678 | 0.86 | TSHR (0.52) | TP53TSHRKMT2AALDH1A1SMN1; SMN2 | |
| Aminobenzoic Acid SCHEMBL5875286 | 0.86 | TSHR (0.52) | TP53TSHRKMT2ANPC1RAB9A | |
| Aminobenzoic Acid SCHEMBL10420842 | 0.86 | TSHR (0.52) | TP53TSHRKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283634-A | Aromatic diamine chain extender containing ester group and preparation method thereof | 江苏湘园化工有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-6403063-B1 | APPLYING POLYUREA; CURING | SAWYER KENNETH I (US) | 2002-06-11 | — | — | US | disclosed |
| US-6401724-B1 | POLYUREA-FORMING COMPOSITION SUCH AS 1)AN AMINOBENZOIC ACID ESTER OR AMIDE OF A POSSIBLY OLIGOMERIC POLYOL OR POLYAMINE OR AN AROMATIC DIAMINE AND 2)A POLYISOCYANATE | PAR PHARMACEUTICALS INCORPORATED | 2002-06-11 | — | — | US | disclosed |
| WO-2000069943-A1 | POLYUREA COMPOSITION | K & L TECHNOLOGIES, INC. (US) | 2000-11-23 | — | — | WO | disclosed |
| EP-0538850-B1 | New polyurea resins and their preparation and use | IHARA CHEMICAL IND CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5319058-A | Improved heat resistance when polyisocyanate component is a combination of an aliphatic diisocyanate and a cyclic trimer of an aliphatic polyisocyanate | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0538850-A2 | New polyurea resins and their preparation and use | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1993-04-28 | — | — | EP | disclosed |